CellD SARL

CARR UFMini® Single-Use Centrifugation

Personalized Medicine with a Single-Use System

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The Pneumatic Scale Angelus’ CARR Centritech UFMini® is the scaled-down version of our UniFuge® single-use centrifuge, designed for harvesting CHO, Stem, and other cells for biotech and pharmaceutical applications. This user-friendly system is intended for use in cleanrooms, in laminar flow hoods, and on benchtops.

The UFMini separation system utilizes a gamma irradiated, single-use module that requires NO CIP and NO SIP.

The single-use module is supplied with a tubeset, which can be readily tube welded to your single-use bioreactor connections (customer-specified single-use connectors available upon request).

The UFMini is completely automated with flexible cycle parameters. The feed suspension is gently pumped to the separation zone of the single use module and the cells centrifugally settle to the outer radius, while the clarified supernatant is continuously discharged. Once the user programmed cycle timer has expired, the controller stops the rotor and discharges the cells. This cycle automatically repeats for a user-selectable number of cycles based upon bioreactor volume.

UNIFUGE Single Use, 1 à 6L/min

• Single-use module (irradiated gamma bowl)

• No CIP (Cleaning in Place) or SIP (Sterilization in Place)

• Fully automated

• High cell harvest rate

• Insect and mammalian cells

• Intuitive software

• Low shear centrifugation

• Maximum cell viability guaranteed

• Advanced design and manufacturing

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The new Unifuge centrifuge system from PneumaticscaleAngelus uses a single-use harvesting module, which is gamma irradiated.

The "Single Use" module is easy to install (less than 10 minutes)
This system guarantees excellent separations with low shear and maximum viability of the harvested cells.

From the moment the cells are not lysed, the production of debris is minimized, making the Unifuge a centrifuge of choice when it comes to both harvesting the cells and / or clarifying the supernatant.

The Unifuge modules are ready to use and equipped with heat-sealable tubes to be sterile connected to your bioreactor and to the collection tanks (custom disposable connectors on request)

The Unifuge is fully automated and recipes allow one or more discharge cycles to be carried out. The suspended material is gently pumped to the module and the cells are concentrated against the outer ring while the supernatant is continuously discharged. Once the module is full, the controller stops the rotor and discharges the cells. This cycle is repeated until the entire volume is processed. Possibility at the end of the cycle to inject a cell cleaning buffer, automatically.

UNIFUGE U2K Single Use, 1 à 20L/min

CARR® Centritech Separation Systems: CARR U2k®

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CARR Centritech’s new U2k single-use centrifuge from Pneumatic Scale Angelus is the scaled-up version of our successful UniFuge® product.

It uses a gamma irradiated, single-use module that requires NO CIP and NO SIP. All process contact surfaces are supplied as one module and are 100% replaceable after each run. U2k® modules are readily tube welded to your single-use bioreactor connections (customer-specified single-use connectors available upon request).

The U2k® is completely automated with flexible cycle parameter entry via touch screen HMI. The feed suspension is gently pumped to the module and the cells settle to the outer radius, while the clear supernatant and concentrate are continuously discharged.

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Continuous Discharge Single-Use Module

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• Tapered rotor to transport cells

• Centripetal pump to evacuate cell paste

• Center feed for low shear operation

• Concentric tubes to introduce feed and remove supernatant and concentrate

• USP Class VI components

• Gamma irradiated

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